A radically different paradigm of physics would result in technologies that can't be imagined in the present paradigm of physics. For example nobody had even remotely guessed that transistors were possible until well in to the development of solid state theory.
we have plenty of unrealized technologies that can be imagined in the present paradigm but that we're not exploiting yet (see for example recent advances in 2D topological materials).
(based on my understanding of transistors, the first ones were conceived before the theory for them existed, and the first ones were built around the same time the quantum theory for them was expressed).