Do you mean tone.js? If so then yes I started out using it, but wound up rolling my own engines. I don't remember specifically why, but something to do with wanting less magic and more low-level control.

I wanted everything to be realtime web audio, so I wound up just building instruments out of oscillators and so on. Here's a very old sample to give the idea:

https://fenomas.com/2017/12/advent-17/