How relevant is the part about running Windows applications through Wine now? I'm under the impression it's less relevant than it used to be, due to web apps now having replaced a lot of native programs, and many native programs are just disguised webapps, like VS Code.
For example, you cannot get a copy of Windows 95/98/ME legally right now. So if a customer is asking you for a copy of your very old software product, maybe a copy running on wine is a good option. It is known that some systems in the world are still using floppy now. In that kind of case, wine with Linux can be seen as an alternative way of using that old illegal copies of Windows.
For modern applications, you do not need to do that. Even though it cannot run on Linux natively, you can always find some alternatives.