Yes. That's a risk assessment every company must make. What's the probability of downtime vs the development slowdown and the operating costs of a fully redundant infrastructure?
I worked for a payments company (think credit cards). We designed the system to maintain very high availability in the payment flow. Multi-region, multi-AZ in AWS. But all other flows such as user registration, customer care or even bill settlement had to stop during that one incident when our main datacenter lost power after a testing switch. The outage lasted for three hours and it happened exactly once in five years.
In that specific case, investing into higher availability by architecting in more redundancy would not be worth it. We had more downtime caused by bad code and not well thought out deployments. But that risk equation will be different for everyone.