I feel like I've tried at least 5 different package management tools for python. Between pip, poetry, pip-tools, pipx, I'm not really sure what easy_install, egg, pkg_info are, but I do know I have always been surprised I need to care.

It sounds like uv is a drop-in replacement for pip, pipx, and poetry with all of their benefits and none of the downsides, so I don't see why I wouldn't migrate to it overnight.