Honestly Chrome is the worst. I'll have 10-12 tabs open (including apps like Asana and Gmail, plus a few extensions) and it takes a while to switch tabs, especially when I'm also doing development work, with Atom open, a few iTerm tabs, Activity Monitor, Finder windows, Messenger, Telegram, and Mail. Add a few daemons for servers or databases running in the background it just locks my system up.

Plus I work with data sets, and my HDD is filling up fast...